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ZoP THE BIS-DI-P-AMINOTOLUENGLYOXIME MONO-P- AMINOTOLUENE TRIHYDRATE WITH ANTIBACTERIAL AND ANTIFUNGALACTIVITY

autorzy: Dumitru URECHE', Ion BULHACI

The invention relates to chemistry, in particular to dioxime bis-di-p-aminotolueneglyoxime mono-p-aminotoluene trihydrate as a polydentate coordination agent for the purpose of new coordinating compounds obtaining with original and supramolecular structure, as well as to microbiology, intended for use as an antibacterial and antifungal remedy. It was synthesized a new coordination agent, obtained from the condensation of p-amino- toluene with dichloroglyoxime In a molar ratio of 2:1. /This coordination agent has been studied as an antibacterial and (antifungal remedy. Non-pathogenic strains of Bacillus subtilis CNMN BB-01, Pseudomonas fluoresces CNMN-PFB-01 and phytopathogenic strains of Xanthomonas campestris, Erwinia amvlovora, Erwinia carotovora were selected as test bacteria for the evaluation of antibacterial activity and as test-fungus strains were selected: Candida utilis and Saccharomuces cerevisiae.