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ZoP MANUFACTURING PROCESS OF A PRODUCT DESTINED FOR BONE DEFECTS RECONSTRUCTION, BASED ON HYDROXIAPATITE AND BIOGENIC BIPHASIC CALCIUM PHOSPHATE
autorzy: Florin MICULESCU, Aura Catalina MOCANU, George STAN, Iulian Vasile ANTONIAC, Mihnea Cosmin COSTOIU, Stefan Ioan VOICU, Marian MICULESCU, Ileana Mariana MATEȘ, Augustin SEMENESCU
The invention relates to the manufacturing process of a product destined for bone defects reconstruction, based on hydroxyapatite and biogenic biphasic calcium phosphate, with a controlled ratio between hydroxyapatite/tricalcium phosphate. All calcium phosphates result from the thermal dissociation of calcium carbonate in form of dolomitic marble and seashells, and treatment of calcium hydroxide solution with phosphoric acid (range: 100−130% x calculated stoichiometric amount).
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